San Francisco Rush 2049 is a racing video game developed and published by Atari Games for arcades and was ported to the Nintendo 64 by Midway Games on September 7, 2000 in North America. It is the third game in the Rush series and the sequel to San Francisco Rush: Extreme Racing and Rush 2: Extreme Racing USA. It is also the last game in the Rush series to be set in the city of San Francisco, and the last released on a Nintendo console. It also serves as the final game for the Atari Games label, which was retired shortly after the arcade release.

The game features an arcade-style physics engine. Tracks are based around a futuristic representation of San Francisco. Cars have the ability to extend wings from their sides, allowing for mid-air adjustments. This feature is a product of the science fiction setting and as such is not seen in other entries in the Rush series. As with previous titles in the franchise, Rush 2049 features a stunt mode in which the player scores points for complex mid-air maneuvers and successful landings. The game also includes a multiplayer deathmatch battle mode and race mode for up to four players. There are six race tracks, four stunt arenas, eight battle arenas, and one unlockable obstacle course named 'The Gauntlet'. Various car types and upgrades are unlockable throughout the game, though cheat codes offer instant achievement of these elements.