NFL Blitz is a series of American football themed video games originally released by Midway featuring National Football League (NFL) teams. It began as a 1997 arcade game NFL Blitz that was ported to home consoles and spawned a series of sequels. Rather than being designed as a realistic interpretation of the sport of football, like Madden NFL or NFL 2K, the Blitz series was created as an over-the-top, exaggerated version of the sport, inspired by Midway's own NBA Jam basketball games.

In 2005, after losing the NFL license, Midway relaunched the Blitz series as Blitz: The League, depicting fictional players and teams in a fictional league with slightly more realistic (though still exaggerated) on-field play and a focus on the seedy behind-the-scenes lives of the players.