Phantasy Star: The End of the Millennium is a role-playing video game developed and published by Sega for the Sega Genesis.

Phantasy Star IV takes place 1,000 years after the events of Phantasy Star II and 1,000 years before the era of Phantasy Star III. After an event called the Great Collapse, much of the once-thriving planet Motavia has reverted back to a desert, and life has become progressively more difficult for the planet's inhabitants. To make matters worse, there has been a marked increase in the numbers of the "biomonsters," a catch-all term for the strange and violent aberrations of Motavia's flora and fauna.