Zack & Wiki: Quest for Barbaros' Treasure is an adventure/puzzle video game published and developed by Capcom for the Wii video game console. It was first released in North America on October 23, 2007, and was later released in Japan, PAL regions, and as one of eight Wii launch games in South Korea. The game stars the aspiring pirate Zack and his monkey friend Wiki. Shortly after joining a pirate gang called "The Sea Rabbits", the pair discovers a talking skull belonging to the pirate captain Barbaros. In exchange for helping find all the pieces of the captain's cursed body, Barbaros promises to lead Zack and Wiki to the coveted "Treasure Island" and his legendary pirate ship.

Inspired by traditional graphic adventure games, Zack & Wiki features a unique way of puzzle-solving by coupling a point-and-click interface with gesture mechanics using the Wii Remote. In each level, the player is tasked with reaching a treasure chest by guiding Zack with an onscreen cursor and then interacting with objects to solve puzzles leading to the treasure. The Remote is used for mimicking actions such as pulling levers, turning keys, and pouring liquids. Shaking the Remote also rings Zack's companion Wiki like a bell, which transforms any nearby enemies into usable tools for solving each level's numerous puzzles. Despite being a commercial failure, Zack and Wiki received highly positive reviews from critics.