Assassin's Creed III is a 2012 action-adventure video game developed by Ubisoft Montreal and published by Ubisoft for Wii U. It is the fifth major installment in the Assassin's Creed series, and a direct sequel to 2011's Assassin's Creed: Revelations.

The plot is set in a fictional history of real-world events and follows the centuries-old struggle between the Assassins, who fight for peace with free will, and the Templars, who desire peace through control. The framing story is set in the 21st century and features series protagonist Desmond Miles who, with the aid of a machine known as the Animus, relives the memories of his ancestors to find a way to avert the 2012 apocalypse. The story is set in the 18th century, before, during and after the American Revolution from 1754 to 1783, and follows Desmond's half-English, half-Mohawk ancestor, Ratonhnhaké:ton, also known as Connor, as he fights the Templars' attempts to gain control in the colonies.

Assassin's Creed III is set in an open world and presented from the third-person perspective with a primary focus on using Desmond and Connor's combat and stealth abilities to eliminate targets and explore the environment. Connor is able to freely explore 18th-century Boston, New York City, and the American frontier to complete side missions away from the primary storyline.