Ken Griffey Jr.'s Winning Run is a baseball video game developed by Rare for the Super Nintendo Entertainment System that is named after the baseball player Ken Griffey Jr.

The game features the 28 MLB teams in existence at the time, though playing through a full 162 game season unlocks the option to play against the two 1998 expansion teams, the Tampa Bay Devil Rays and the Arizona Diamondbacks. The game includes a franchise mode, MLB Challenge mode, exhibition (single-game) play, and All-Star Game mode, which includes a home run derby mode. Unlike its predecessor, most of the stadiums in the game are generic and the Houston Astros play on natural grass at the Astrodome. From the batter's box most of the other stadiums look authentic but once the ball goes towards the warning track, the outfield walls on either side have a big wall and left center/centerfield/right center have a small outfield wall. At Wrigley Field the ivy is visible from the batters box, but once the ball goes towards the outfield wall there is no signature green ivy.