Gradius III is a 1989 scrolling shooter video game developed and published by Konami.

The player pilots the starfighter Vic Viper starfighter to battle the onslaughts of the Bacterion Empire. There are a total of ten levels in the game, with stage 4 being something of a bonus level; here, the player controls the Vic Viper in a third-person perspective and must avoid colliding with walls. Though the level is completely devoid of any enemies, free floating power-ups are scattered throughout. There are also two hidden levels that are based on the early sections of Gradius and Salamander. The game contains the familiar weapons, level layouts, and enemies that have become trademarks of the series.

Unlike previous games in the series, Gradius III does not include a continuation feature; if the player loses their lives, the game will be over. The Japanese version of the game contains a 'beginner mode' that allows the player to venture through the first three levels at a much easier difficulty. At the end of the third level, the game will bid the player to try the game again at the normal difficulty ('technical mode'), which can loop endlessly. The Asian and Worldwide arcade releases lack the beginner mode and retrospective introduction sequence, but reduce the difficulty overall.