Ready 2 Rumble Boxing is a boxing video game developed by Midway Studios San Diego, published by Midway Games in 1999 for the Nintendo 64. Like Nintendo's Punch-Out!! series, it features many characters with colorful personalities (i.e. Afro Thunder, Boris "The Bear" Knokimov, etc.); however, unlike the Punch-Out!! series, Ready 2 Rumble Boxing is in 3D, thus allowing for more control over one's character in the ring. Also unlike Punch-Out!!, players can choose whichever boxer they want from a rather large selection of characters.

Throughout the fights in the game, there is a special RUMBLE meter which fills up, one or two letters at a time, until the word "RUMBLE" is spelled at the bottom of the screen. Letters can be obtained by successfully landing hard blows; most such actions will yield one letter, though some particularly strong punches may yield more. Once the meter is full, the player can power himself up, enabling access to a special combo called "Rumble Flurry", activated by pressing a button combination. Each character's "flurry" is unique to them, and consists of a series of punches which does a large amount of damage if landed successfully.