Earthworm Jim 2 is a run and gun platform video game and the sequel to Earthworm Jim, and the second and final game in the Earthworm Jim series developed by original creators Doug TenNapel, David Perry, and Shiny Entertainment.

The purpose of the game is largely the same as it was in the original Earthworm Jim; traverse through the levels in order to save Princess What's Her Name from Psy-Crow. However, gameplay is much more diverse than in the original game.

While the majority of levels are still based on run and gun and platform game elements, separate levels incorporate different gameplay elements as well. Some levels, such as the opening level, "Anything But Tangerines", and the game's eighth level, "Level Ate", play largely the same as the original Earthworm Jim, with the exception of there being a larger variety of moves at the players disposal. For instance, there are more types of guns to use once found in a level, such as an auto-aiming gun, or the "Barn Blaster" gun which takes out every enemy visible on the screen. Additionally, Jim's friend, Snott, travels with him and can be used to stick and swing to other slimy green surfaces or as a parachute upon jumping.